Sphingolipid cofactors
نویسندگان
چکیده
منابع مشابه
Surprising cofactors in metalloenzymes.
Transition metal complexes are located at the active sites of a number of enzymes involved in intriguing biochemical reactions. These complexes can exhibit a wide variety of chemical reactivity due to the ease at which transition metals can adopt different coordination environments and oxidation states. Crystallography has been a powerful technique for examining the structure and conformational...
متن کاملWaltzing around cofactors
The metallocofactor involved in fixing nitrogen is not a rigid scaffold, as was previously thought.
متن کاملKeeping sphingolipid levels nORMal.
L ipids are essential for life as the principal components of biomembranes. In addition, many lipids act as signaling molecules both in and outside the cell. For these structural and regulatory functions it is crucial that the abundance of different lipids is controlled in a coordinated fashion to maintain the right balance between them. Aberrations in this equilibrium could result in altered m...
متن کاملAntioxidant Molecules and Redox Cofactors
2.1. Glutathione 2.1.A. Biological Functions 2.1.B. Biosynthesis 2.1.C. Degradation 2.1.D. Other Thiol-Based Redox Buffers 2.2. Ascorbate 2.2.A. Ascorbate Chemistry 2.2.B. Ascorbate Biosynthesis 2.2.C. Ascorbate Recycling 2.2.D. Ascorbate Transport 2.2.E. Importance of Ascorbate in Stress and Disease 2.3. Other Antioxidants 2.3.A. Lipid-Soluble Antioxidants 2.3.B. Water-Soluble Antioxidants 2.3...
متن کاملRibozymes that use redox cofactors *
This review summarizes the history and most recent advances in aptamers and ribozymes that bind and use redox(reduction–oxidation) cofactors. Redox reactions, catalyzed by protein enzymes in an extant world, play a central role in the metabolism of numerous biological molecules in the living organisms. The burden of catalyzing these reactions in a preprotein-based world (i.e., the hypothesized ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Chemical Biology
سال: 2012
ISSN: 1552-4450,1552-4469
DOI: 10.1038/nchembio.945